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Chromatin stability safeguards mitochondrial homeostasis and restrains TORC1 signaling

Vinoth Sigamani et al.
PLOS · Papers · License: CC BY 4.0
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cell-deathchromatindna-methylationmitochondria
Chromatin is dynamically regulated in response to nutrient flux to promote the transcriptional changes needed for adaptation. The mechanistic target of rapamycin complex 1 (yeast TORC1) kinase integrates nutrient signaling with chromatin regulation, yet whether chromatin signals back to regulate TO
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