bioRxiv / medRxiv
open access
CC BY 4.0
Perturbation-Aware Neural ODE (pNODE) Learns Microbiome Dynamics from Clinical Data and Predicts Gut-Borne Bloodstream Infections in Patients Receiving Cancer Treatment
Disruption of the gut microbiota during cancer treatment, particularly in allogeneic hematopoietic cell transplantation (allo-HCT), contributes to adverse clinical outcomes, including gut-borne bloodstream infections. Accurately forecasting microbial population dynamics under clinical perturbations,
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