bioRxiv / medRxiv
open access
CC BY 4.0
PrEditR: A protein-centric platform for CRISPR-mediated base editor sgRNA design
Motivation: Post-translational modifications (PTMs) are critical to protein activity, yet the biological role of most known modification sites remains uncharacterized. CRISPR-mediated phenotypic screens using base editors offer a powerful approach to dissecting PTM function at scale. However, existi
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