bioRxiv / medRxiv
open access
CC BY-NC-ND 4.0
Phenotypic illusion but genetic decoupling between osteoarthritis and Parkinson's disease
Observational studies have repeatedly linked osteoarthritis (OA) with Parkinsons disease (PD), but whether this reflects causality, shared genetic architecture, or artefactual mechanisms remains unresolved. We triangulated six layers of evidence: two population cohorts, genome-wide and local genetic
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