Pharmacovigilance of Integrase Strand Transfer Inhibitors (INSTIs) in Botswana: Safety Signals, Report Completeness, and Causality Assessment

Integrase strand transfer inhibitors (INSTIs) are the preferred first-line anchor drug for antiretroviral therapy globally. However, post-marketing authorisation studies continue to find previously unidentified adverse events (AEs) associated with INSTIs. A pharmacovigilance study was conducted to i