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Identification of Plasmodium falciparum var1CSA and var2CSA domains that bind IgM natural antibodies

Jean-Philippe Semblat et al.
HAL (France) · Papers
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Malaria in pregnancy is responsible for maternal anaemia, low-birth-weight babies and infant deaths. Plasmodium falciparum infected erythrocytes are thought to cause placental pathology by adhering to host receptors such as chondroitin sulphate A (CSA). CSA binding infected erythrocytes also bind Ig
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