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Identification of the minimal binding region of a Plasmodium falciparum IgM binding PfEMP1 domain

Jean-Philippe Semblat et al.
HAL (France) · Papers
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Binding of host immunoglobulin is a common immune evasion mechanism demonstrated by microbial pathogens. Previous work showed that the malaria parasite Plasmodium falciparum binds the Fc-region of human IgM molecules, resulting in a coating of IgM on the surface of infected erythrocytes. IgM binding
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