HAL (France)
open access
Astrocytic uptake of neuronal corpses promotes cell-to-cell spreading of tau pathology
Abstract Tau deposits in astrocytes are frequently found in Alzheimer’s disease (AD) and other tauopathies. Since astrocytes do not express tau, the inclusions have been suggested to be of neuronal origin. However, the mechanisms behind their appearance and their relevance for disease progression re
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