bioRxiv / medRxiv
open access
Dengue virus-induced thrombocytopenia is mediated by dysregulation of the RUNX1-MYH9 axis
Dengue virus (DENV) infection causes an acute febrile illness that is usually self-limiting but can become fatal. Thrombocytopenia, or a decrease in circulating platelets, is a major clinical feature of dengue and is strongly associated with the progression to dengue hemorrhagic fever and dengue sho
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