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Phenotypic screens identify biologic regulators of nanoparticle uptake in diffuse midline glioma

Cheng, E. L. et al.
bioRxiv / medRxiv · Papers
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bioengineering
Nanoparticle drug delivery systems hold considerable promise for locoregional administration to central nervous system tumors, yet the biological determinants of nanoparticle-cancer cell interactions remain poorly understood. Using patient-derived histone-mutant diffuse midline glioma (DMG) models,
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