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Biocatalytic Production of Galantamine in Yeast through Cytochrome P450 Optimization

Holtz, M. et al.
bioRxiv / medRxiv · Papers
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synthetic-biology
Galantamine is a pharmaceutically relevant Amaryllidaceae alkaloid used for the treatment of Alzheimer's disease. Its structural complexity and low abundance in plants motivate the development of alternative manufacturing routes. Here, we established the first engineered yeast platform for the bioca
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