bioRxiv / medRxiv
open access
The Principal Component Life Trajectory (PCLT): Mapping Sex-Specific Physiological Change Across the Human Lifespan
Age- and sex-related variation in physiological biomarkers is well documented, yet how coordinated systemic physiology unfolds across life stages at the population level remains unclear. Here, we introduce the Principal Component Life Trajectory (PCLT), reconstructing physiological trajectories via
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