bioRxiv / medRxiv
open access
Cell-composition sensitivity of pooled whole-blood DNA methylation profiling in sepsis using the Infinium MethylationEPIC v2.0 array and SeSAMe
ObjectiveTo characterize pool-level methylation differences associated with sepsis and examine their sensitivity to estimated leukocyte composition using the Infinium MethylationEPIC v2.0 array. DesignSingle-center pilot epigenome-wide association study (EWAS) of pooled genomic DNA, analyzed at the
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