bioRxiv / medRxiv
open access
Multi-trait Polygenic Profiling and Survival Free of Dementia and Disability: Results from the Health and Retirement Study
ObjectiveTo determine whether a multi-trait polygenic profile for dementia is associated with dementia- and disability-free survival in middle-aged and older adults. BackgroundClinical trials of brain health and aging increasingly use holistic, patient-centered outcomes that capture overall health
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