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Pectin Intervention Study and Long-term Follow-up in Lipid Transfer Proteins Allergic Patients

Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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immunomodulationmicrobiomena
Pectins are dietary fibers that have shown a health effect on patients with food allergy, as they are capable of modifying the composition of gastrointestinal microbiota, and producing an immunomodulatory effect. Preliminary results by the investigators show that the intervention for 2 months with pectins produces an increase in tolerance to peach, and changes in the microbiota compared to the group of patients treated with placebo. In this project, the investigators aim to study these clinical effects and the involved mechanisms. Moreover, the long-term effect (clinical reactivity to nsLTP and immunomodulatory effect) of the dietary intervention will be prospectively evaluated 6 months after the intervention.
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