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Effect of Single High Dose of Cholecalciferol on Serum Metabolites of Vitamin D

Department of Endocrinology, Centre of Postgraduate Medical Education · 2021
ClinicalTrials.gov · Datasets · License: Public Domain · 2021
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vitamin-dvitamin-d-deficiency
The aim of this interventional study is to assess the effect of the single high dose of vitamin D on its serum metabolites in elderly. The main questions it attempts to answer is: 1. what is the effect of a single, high, oral dose of vitamin D3 (120,000 IU) on serum 25(OH)D3, 25(OH)D2, 24,25(OH)2D3, 3-epi-25(OH)D3, 1,25(OH)2D3, 24,25(OH)2D3/25(OH)D3 ratio, and 25(OH)D3/3-epi-25(OH)D3 ratio concentration at baseline, 3 days and 7 days after administration, compared to control group. 2. what is the influence of percentage of fat tissue on serum metabolites of vitamin D and their changes after bolus dose, compared to control group.
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