Genetic Studies of Non-Alcoholic Fatty Liver Disease

Background: \- Non-alcoholic fatty liver disease is the most common form of liver disease in the United States. It includes many conditions. Researchers want to study fatty liver disease by looking at people who have liver cirrhosis. They also want to look at people who are or were listed for liver transplants. Genetic studies may provide more information on the causes of these conditions. Objectives: \- To study possible genetic causes of non-alcoholic fatty liver disease. Eligibility: \- Individuals of any age who have non-alcoholic fatty liver disease and related conditions. Design: * Participants will be screened with a physical exam and medical history. * Participants will provide a blood sample for genetic testing. Liver tissue from a transplant or biopsy may also be studied. * Participants may also be asked to have an imaging study of the liver. This imaging study may be an x-ray or magnetic resonance imaging. * No treatment will be provided as part of this research study.