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Phase I/II Study of Immune Therapy After Allograft in Patients With Myeloid Hemopathy

Institut Paoli-Calmettes · 2013
ClinicalTrials.gov · Datasets · License: Public Domain · 2013
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acute-myeloid-leukemiaallograft
Patients with acute or chronic myeloid leukemia, or myelodysplastic syndrome, underwent allogeneic stem cell transplantation from HLA-identical donor (related or unrelated) after reduced-intensity conditioning regimen. If WT1 expression is detectable on tumor cells, they will receive an immune therapy 60 days after allograft. 6 administrations every 2 weeks of the protein recwt1-A10+AS01B will be administrated. The safety and immunological efficacy of this immune therapy after hematopoietic stem cells transplantation with reduced intensity conditioning will be evaluated.
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