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HDP vs NS Intra-articular Injection Among KOA With Obese Patient

Rumah Sakit Umum Daerah Haji Provinsi Jawa Timur, Indonesia · 2023
ClinicalTrials.gov · Datasets · License: Public Domain · 2023
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knee-osteoarthritisnaobesity
The aim of this randomized controlled trial study was to compare the effect of intra-articular injection of Hypertonic Dextrose Prolotherapy (HDP) with Normal Saline (NS) in the clinical improvement of knee osteoarthritis (KOA) patients with comorbid obesity. The main questions to be answered are: * How does the effect of HDP versus NS intra-articular injection compare to the numerical rating score (NRS) in obese KOA patients? * How does the effect of HDP versus NS intra-articular injection compare to scores of The Western Ontario and McMaster Universities Arthritis Index (WOMAC) in obese KOA patients? * How does the effect of HDP versus NS intra-articular injection compare to the thickness of the femoral cartilage in obese KOA patients? Participants who meet the inclusion and exclusion criteria will be randomized based on the order of the outpatient department each day, with odd numbers as the HDP intervention group and even numbers as NS. They received ultrasound-guided intra-articular injections on day 1 and day 30. Researchers will compare HDP versus NS groups to see which group improves NRS, WOMAC, and femoral cartilage thickness.
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