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mtDNA depletion‐like syndrome in Wilson disease

Medici, Valentina et al.
eScholarship · Papers
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BACKGROUND AND AIMS: Wilson disease (WD) is caused by mutations in the copper transporter ATP7B, with its main pathology attributed to copper-mediated oxidative damage. The limited therapeutic effect of copper chelators and the early occurrence of mitochondrial deficits, however, undermine the preva
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