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Spatiotemporal Control of Vascular CaV1.2 by α1C S1928 Phosphorylation

Baudel, Miguel Martín-Aragón et al.
eScholarship · Papers · License: CC BY-NC-ND
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BACKGROUND: L-type CaV1.2 channels undergo cooperative gating to regulate cell function, although mechanisms are unclear. This study tests the hypothesis that phosphorylation of the CaV1.2 pore-forming subunit α1C at S1928 mediates vascular CaV1.2 cooperativity during diabetic hyperglycemia. METHODS
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