HAL (France)
open access
Listeria promotes systemic infection by targeting the host deubiquitinase CYLD
Abstract Listeria monocytogenes ( Lm ) is an intracellular pathogen that can cause life-threatening systemic infections. Internalin C (InlC) is a secreted factor required for full Lm virulence in systemic models of infection by mechanisms that remain unclear. Here, we show that InlC binds to CYLD, a
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