bioRxiv / medRxiv
open access
Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death
Cells must adapt to environmental changes to maintain homeostasis. One of the most striking environmental adaptations is entry into hibernation during which core body temperature can decrease from 37C to as low at 4C. How mammalian cells, which evolved to optimally function within a narrow range of
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