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Serum Concentrations of Antidepressant Drugs in Pregnant Women - a Naturalistic Study

Linkoeping University · 2011
ClinicalTrials.gov · Datasets · License: Public Domain · 2011
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pharmacokineticspregnancy
The study was a prospective naturalistic PK study of five frequently used antidepressant drugs in pregnant women; citalopram (CIT), escitalopram (ECIT), sertraline (SERT), mirtazapine (MIRT) and venlafaxine VEN) and their major metabolites (Table 1). After signing informed consent pregnant women with ongoing antidepressant treatment, regardless of indication, were recruited at nine antenatal care centers in mid- and small cities and villages in the Southeast Sweden between April 2011 and September 2013.
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