eScholarship
metadata only
CC BY-NC-SA
B-1 plasma cells require non-cognate CD4 T cell help to generate a unique repertoire of natural IgM
Evolutionarily conserved, "natural" (n)IgM is broadly reactive to both self and foreign antigens. Its selective deficiency leads to increases in autoimmune diseases and infections. In mice, nIgM is secreted independent of microbial exposure to bone marrow (BM) and spleen B-1 cell-derived plasma cell
Conceptio Open Archive
Analyze & explore related research in Conceptio
Connect this record directly into your research workflow or AI agent. Explore citations across open repositories, query full text, and export structured proof bundles.
This document is indexed with metadata only: full text is not available in the archive for this record. Open the official source ↗
Related documents
- Beyond B cells: T and Innate Immune Mechanisms of Autoimmunity in Common Variable Immunodeficiency.#615734
- T and B Cell Responses in Autoimmune Diseases#160277
- The pathogenic role of double-negative B cells in autoimmune diseases.#446101
- VDJ-recombination of the B-cell Receptor Following Hematopoietic Stem Cell Transplantation#1280075
- Mapping the Altered Landscape of TCR Repertoire in Autoimmune Diseases.#659573
Record · ID 1298571
Retrieved via Conceptio: every document is proof-bundled with source, license, and retrieval metadata.
Retrieved via Conceptio: every document is proof-bundled with source, license, and retrieval metadata.
Bring this data into your agent: Connect via MCP or API · 20 free credits to start · no card required
Read the Docs → · View CLI source on GitHub · Conceptio Open Knowledge Archive
Read the Docs → · View CLI source on GitHub · Conceptio Open Knowledge Archive