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Carotid Web and Stroke Registry.

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · 2022
ClinicalTrials.gov · Datasets · License: Public Domain · 2022
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stroke
Introduction: Carotid Web (CW) is a common cause of stroke in young patients with a high recurrence rate. The factors associated with recurrences and the appropriate treatment to prevent them are currently unknown. Main objective: To compare recurrences of ischemic stroke (cerebral infarction or transient ischemic attack) in patients with CW according to the preventive treatment. Secondary objectives: * To describe the frequency of recurrences in patients with stroke and CW. * To compare the risk of complications, especially hemorrhagic complications, in patients with stroke and CW according to the type of preventive treatment given. * To describe the clinical and radiological characteristics of CW and identify which are associated with recurrences. * To detect genetic polymorphisms associated with the presence of CW in stroke patients. Study design: Multicenter, prospective registry of consecutive cases with ischemic stroke in which a Carotid Web is detected between 2022 and 2024. All patients with ischemic stroke or transient ischemic attack and age \> or = 18 years, in whom a Carotid Web is diagnosed, will be included. Demographic and clinical variables, genetic study (not mandatory), diagnostic methods of CW, reperfusion treatment and secondary prevention will be collected. During a minimum follow-up of six months, vascular events (stroke, transient ischemic accidents, cerebral hemorrhages) and treatments (antiplatelet therapy, anticoagulation, endarterectomy, endovascular therapy) will be collected. Once the registry has been completed, the frequency of recurrences and the factors associated with them will be analyzed. Study population: Patients with ischemic stroke or transient ischemic attack in whom a Carotid Web is detected. It is estimated to obtain data from approximately 100 patients. Variables: Demographic, clinical (past medical history, stroke characteristics), radiological (diagnostic method of CW, morphological characteristics of CW), t
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