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Psychobiological Markers to Improve Diagnosis and to Predict Affective Episodes in Bipolar Disorder

Karolinska Institutet · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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activitybipolar-disordercognitionmajor-depressive-disordermood-disorderssleep
This trial has two studies. In study 1, the investigators will explore the relationships between three psychobiological factors (sleep patterns, motor activity, and decision-making ability). The investigators aim to investigate how these factors interact in BD patients. This understanding will facilitate the distinction of BD patients from patients with recurrent depressive disorder (MDD) and healthy controls. In study 2, the investigators will continue following patients with bipolar disorder and use the interplay between the three psychobiological factors to develop early markers of full-blown affective episodes.
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