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Disease-Associated Short Tandem Repeats Co-localize with Chromatin Domain Boundaries

Sun, James H et al.
eScholarship · Papers
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31-biological-sciences-for-2020
More than 25 inherited human disorders are caused by the unstable expansion of repetitive DNA sequences termed short tandem repeats (STRs). A fundamental unresolved question is why some STRs are susceptible to pathologic expansion, whereas thousands of repeat tracts across the human genome
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