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Transcriptional down-regulation of ccr5 in a subset of HIV+ controllers and their family members

Gonzalo-Gil, Elena et al.
eScholarship · Papers · License: CC0 1.0
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HIV +Elite and Viremic controllers (EC/VCs) are able to control virus infection, perhaps because of host genetic determinants. We identified 16% (21 of 131) EC/VCs with CD4 +T cells with resistance specific to R5-tropic HIV, reversed after introduction of ccr5. R5 resistance was not observed in macr
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