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A DEAD-Box Helicase Mediates an RNA Structural Transition in the HIV-1 Rev Response Element

Hammond, John A et al.
eScholarship · Papers
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31-biological-sciences-for-20203107-microbiology-for-2020
Nuclear export of partially spliced or unspliced HIV-1 RNA transcripts requires binding of the viral protein regulator of expression of virion (Rev) to the Rev response element (RRE) and subsequent oligomerization in a cooperative manner. Cellular DEAD-box helicase DEAD-box protein 1 (DDX1) plays a
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