HAL (France)
open access
A new class of scorpion toxin binding sites related to an A‐type K + channel: pharmacological characterization and localization in rat brain
A new scorpion toxin (3751.8 Da) was isolated from the Buthus martensi venom, sequenced and chemically synthesized (sBmTX3). The A‐type current of striatum neurons in culture completely disappeared when 1 μM sBmTX3 was applied ( K d =54 nM), whereas the sustained K + current was unaffected. 125 I‐sB
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