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The correlation of airway obstruction and emphysema on high resolution computed tomography (HRCT) thorax with spirometry in severe chronic obstructive pulmonary disease (COPD)
Background: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease which involves both pulmonary and extrapulmonary components. The pulmonary component is due to airflow limitation, due to parenchymal destruction (emphysema), and airway changes that is partially reversible and usual
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