bioRxiv / medRxiv
open access
Septin inhibitors exert opposing effects on distinct higher-order septin structures in melanoma cells
Septins are cytoskeletal GTPases that assemble into diverse higher-order structures with context-dependent mechanical and signaling functions. Recent work identified a septin-dependent pro-survival pathway in metastatic cancer cells, termed bleb signaling, in which plasma membrane blebbing promotes
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