Spectroscopic identification of gauche and trans conformers in L-phenylalanine Fiber and hydrogel via CH/CD stretching vibrations

Weak molecular interactions and subtle conformational variations can directly modulate C-H bond strength, yet their spectroscopic signatures as a probe of polymorphism remain largely unexplored. Here, chiral phenylalanine in anhydrous Form I, hemi-hydrated fiber, and hydrogel states were investigate