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Topical febuxostat attenuates imiquimod-induced psoriasiform dermatitis and modulates NFE2L2 (NRF2)/NLRP3 mRNA expression
Background: Psoriasis is a chronic immune-mediated inflammatory skin disease characterized by excessive keratinocyte proliferation, persistent oxidative stress, and dysregulated inflammatory responses. Increasing evidence suggests that impaired antioxidant defenses and altered NLRP3-associated in
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