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Validation of a Deep Learning Tool for Opportunistic Osteoporosis Screening Using Routine Non-Contrast CT Scans

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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bone-mineral-densityopportunistic-screeningosteoporosis
The goal of this clinical trial is to test if an artificial intelligence (AI) tool called DeepBMD can accurately identify people at high risk for osteoporosis using routine chest or abdomen CT scans. The main questions it aims to answer are: 1. Can the DeepBMD tool correctly identify people who have osteoporosis compared to the standard bone density test, dual-energy X-ray absorptiometry (DXA)? 2. Is it practical to use this AI tool in real-world hospital settings to find and contact high-risk patients? Researchers will use the DeepBMD tool to analyze existing CT scans. If the tool flags a patient as high risk, researchers will call them to invite them for a standard bone density test (DXA). Participants will: 1. Have their existing chest or abdomen CT scan analyzed by the DeepBMD AI tool; 2. Receive a phone call from the research team if identified as high risk; 3. Visit the clinic for a free standard bone density test (DXA) if they agree to participate.
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