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CpG Methylation Profiles of HIV-1 Proviral DNA in Individuals on ART

Boltz, Valerie F et al.
eScholarship · Papers · License: CC BY
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31-biological-sciences-for-20203107-microbiology-for-2020
The latent HIV-1 reservoir is comprised of stably integrated and intact proviruses with limited to no viral transcription. It has been proposed that latent infection may be maintained by methylation of pro-viral DNA. Here, for the first time, we investigate the cytosine methylation of a replication
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