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A reproducible three-dimensional model of human brain tissue to investigate physiological and disease-associated microglia phenotypes

Klimmt, Julien et al.
Open Access LMU · Papers · License: CC BY 4.0
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Stem-cell-based in vitro models offer promising potential to elucidate human brain cell functions and interactions, but limitations in reproducibility, maturation and cell-type diversity persist. Especially, prolonged incorporation of mature microglia and studies of neuroinflammation have proven cha
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