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Conjugate vaccines targeting tumour vasculature: CLEC14A and ROBO4 as novel immunotherapeutic antigens
Tumour angiogenesis plays a fundamental role in the progression of solid tumours and their metastasis through the leaky vasculature, supplying nutrients and oxygen via these vessels. Targeting tumour endothelial markers (TEMs) such as CLEC14A and ROBO4 presents a promising immunotherapeutic strategy
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