bioRxiv / medRxiv
open access
Structural heterogeneity of CTE Type I tau filaments with an interface-shifted polymorph
Tau filament types can differ in inter-protofilament packing while sharing the same protofilament fold. Motivated by our recent findings in vacuolar tauopathy, we analyzed cryo-electron microscopy (cryo-EM) data from brain-derived chronic traumatic encephalopathy (CTE) tau filaments deposited in EMP
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