bioRxiv / medRxiv
open access
Systematic Profiling of Essential Fungal Transcriptional Regulators Uncovers Ezt1 as a Central Pathobiological and Morphogenic Regulator in Cryptococcus neoformans
Cryptococcus neoformans is a global fungal pathogen that causes fatal cryptococcosis, and the limitations of current antifungals underscore the urgent need for new therapeutics. Here we systematically investigate essential transcriptional regulators in C. neoformans as potential antifungal targets,
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