Conceptio › Archive › ClinicalTrials.gov
ClinicalTrials.gov public full text Public Domain

Management of Post-Induction Hypotension in Emergency Abdominal Surgery

Hopital Charles Nicolle · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
Open Source ↗
The goal of this clinical trial is to compare the efficacy of two vasopressors (norepinephrine vs. ephedrine) in treating hypotension in adult patients (aged 18+, ASA I-III) undergoing general anesthesia for abdominal surgical emergencies (e.g., appendicitis, intestinal obstruction, peritonitis). The main questions it aims to answer are: * Which drug is more effective at maintaining intraoperative blood pressure (SBP ≥ 80% of baseline)? * How many boluses of each vasopressor are required to maintain target blood pressure? Researchers will compare the norepinephrine group (receiving 10 µg boluses) to the ephedrine group (receiving 6 mg boluses) to see if norepinephrine is superior for maintaining hemodynamic stability and reduces the number of interventions needed. Participants will: * Be randomly assigned to receive one of the two study drugs. * Undergo standard general anesthesia with close hemodynamic monitoring. * Receive boluses of the assigned vasopressor whenever their blood pressure drops below a predefined threshold.
Conceptio Open Archive

Analyze & explore related research in Conceptio

Connect this record directly into your research workflow or AI agent. Explore citations across open repositories, query full text, and export structured proof bundles.

This document is indexed with metadata only: full text is not available in the archive for this record. Open the official source ↗

Related documents

Record · ID 1350556
Retrieved via Conceptio: every document is proof-bundled with source, license, and retrieval metadata.
Bring this data into your agent: Connect via MCP or API · 20 free credits to start · no card required
Read the Docs → · View CLI source on GitHub · Conceptio Open Knowledge Archive