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Fever In Palliative Care

Stefania Cheli · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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feverpalliative-care
The goal of this observational study is to evaluate the frequency and characteristics of fever in terminally ill adult patients admitted to the Infectious Diseases Hospice at Luigi Sacco Hospital in Milan. The main questions it aims to answer are: * How often does fever occur in terminally ill patients during hospice care? * What are the typical features of fever in this population in terms of intensity, duration, possible causes, and treatment strategies? * Is there any correlation between the occurrence of fever and patients' clinical characteristics, such as age, sex, BMI, comorbidities, and palliative prognostic scores (PPS and PPI)? Participants will be adult patients (≥18 years) with a life expectancy of more than 24 hours and less than 3 months. During their stay, the following data will be collected: * Presence and characteristics of fever (temperature, duration, treatment, suspected cause) * Clinical and demographic information (e.g., age, sex, BMI, comorbidities, performance status) * Details on hospitalization (e.g., symptom burden, need for palliative sedation, outcome) The study will enroll approximately 250 patients consecutively over a 48-week period. No additional procedures or treatments beyond standard clinical care will be required.
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