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The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor Cells

Radboud University Medical Center · 2018
ClinicalTrials.gov · Datasets · License: Public Domain · 2018
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immunosuppressionmonocytesnasepsis
We will investigate whether human endotoxemia induces changes in human bone marrow cells and their downstream effector cells. To comprehensively investigate underlying mechanisms behind functional and transcriptional changes in these cell types, we will use state-of-the-art systems biology techniques, including single cell transcriptomics (epi)genetics, and metabolomics.
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