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ASA Patterns for Prevention of Preeclampsia in SLE Pregnancies

McGill University Health Centre/Research Institute of the McGill University Health Centre · 2018
ClinicalTrials.gov · Datasets · License: Public Domain · 2018
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adverse-pregnancy-outcomesnapre-eclampsiapregnancy-complicationssle
Preeclampsia is a serious maternal condition affecting up to 5% of pregnancies from the general population and up to 30% of lupus pregnancies. Aspirin (acetylsalicylic acid- ASA) has been shown to reduce the risk of preeclampsia, by half, in women at high risk. Therefore, it is recommended that health professionals initiate aspirin early during pregnancy in women with lupus. Despite this recommendation, there are currently no studies of aspirin in women with lupus for this indication. This is a critical knowledge gap as aspirin could potentially have a large benefit in this high-risk population. The investigator will perform a RCT to evaluate the effect of a specifically designed patient educational tool on preeclampsia knowledge and ASA adherence in pregnant women with SLE. The research efforts will improve reproductive health of SLE women and the outcomes of offsprings.
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