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Smad7-based biologic targeting epidermis and stroma promotes healing of diabetic wounds in mice and pigs

Ke, Yao et al.
eScholarship · Papers · License: CC BY-NC-ND
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31-biological-sciences-for-2020
Diabetic wounds have limited effective therapies to restore tissue repair and resolve excessive inflammation. This study aimed to identify mechanisms of diabetic wound healing defects and test a therapeutic intervention using diabetic mouse and pig models. Here, we show that Smad7 transgene expressi
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