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Enantioselective Synthesis of Isotopically Labeled Homocitric Acid Lactone

Moore, Jared T et al.
eScholarship · Papers
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alcoholism
A concise synthesis of homocitric acid lactone was developed to accommodate systematic placement of carbon isotopes (specifically (13)C) for detailed studies of this cofactor. This new route uses a chiral allylic alcohol, available in multigram quantities from enzymatic resolution, as a starting mat
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