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UHRF1 establishes crosstalk between somatic and germ cells in male reproduction

Wu, Yanqing et al.
eScholarship · Papers · License: CC BY
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31-biological-sciences-for-2020
Sertoli cells (SCs) support and nourish germ cells (GCs) through their crosstalk during spermatogenesis. However, the underlying epigenetic mechanism that ensures SCs’ functions in this process remains unclear. Here, we report that UHRF1, a critical epigenetic regulator, is mainly expressed in human
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