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Sex and APOE genotype specific brain regional vulnerability to Alzheimer's Disease

Zeng Q et al.
Europe PMC · Papers
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alzheimer-s-diseasediffusion-tensor-imagingsex
Alzheimer's disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data
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