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Gas chromatographic-mass spectrometric analysis of captopril and its application in pharmacokinetic studies in healthy subjects
Captopril is a highly specific competitive inhibitor of the angiotensin-convening enzyme (ACE). This enzyme converts angiotensin I, a relatively inactive decapeptide, to angiotensin II , a potent endogenous vasoconstrictor substance. Captopril is widely used for the treatment of hypertension and con
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